• Feb 23 2025

Frequent detection of enterovirus D68 and rhinovirus type C in children with acute respiratory infections

Frequent detection of enterovirus D68 and rhinovirus type C in children with acute respiratory infections

Sayed-Hamidreza Mozhgani 1 2Mohsen Keshavarz 3Neda Mousavi 4Haideh Namdari 5Vahid Salimi 4Talat Mokhtari-Azad 4Mohadeseh Zarei-Ghobadi 6Seyed Alireza Nadji 7Nastaran Ghavami 4Farhad Rezaei 8

Abstract

This study aimed to evaluate the prevalence of human rhinoviruses (HRVs) and the emergence of enterovirus D68 (EV-D68) in children. A total of 322 nasopharyngeal swab samples were provided from children with an initial diagnosis of upper and lower respiratory tract infections. A total of 34 and 70 cases were positive for EV-D68 and HRV, respectively. The phylogenetic analysis revealed that the clades A and B are the prevalent genotypes for EV-D68 and the HRV-positive samples belong to three types including HRV-A, HRV-B, and HRV-C. The results showed that EV-D68 and HRV-C are circulating in Iran especially in the winter.

Keywords: EV-D68; Emerging disease; Genotyping; HRV; Human enterovirus D68; Human rhinoviruses

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